Original Research

Physiology and pathophysiology of cell organelles

J. J. Theron, N. Claasen, A. Panzer, N. Lizamore
Suid-Afrikaanse Tydskrif vir Natuurwetenskap en Tegnologie | Vol 16, No 1 | a656 | DOI: https://doi.org/10.4102/satnt.v16i1.656 | © 1997 J. J. Theron, N. Claasen, A. Panzer, N. Lizamore | This work is licensed under CC Attribution 4.0
Submitted: 11 July 1997 | Published: 11 July 1997

About the author(s)

J. J. Theron,, South Africa
N. Claasen,, South Africa
A. Panzer,, South Africa
N. Lizamore,, South Africa

Full Text:

PDF (476KB)

Share this article

Bookmark and Share

Abstract

Lysosomes are found in the cytoplasm of all eucaryotic cells except mature red blood cells. The matrix of the organelle is separated from the surrounding cytoplasm by a trilaminar unit membrane and contains a variety of acid hydrolytic enzymes. Morphologically primary (recently formed from the Golgi-complex) are distinguished from secondary lysosomes. The latter type is formed after fusion of a vacuole with a primary lysosome and is ultrastructurally extremely heterogeneous due to the large variety of substrates (macro­ molecules ) incorporated in the matrix of the organelle. The acid hydrolases of lysosomes are divided into the following five groups: phosphatases, nucleases, polysaccharide- and glycosaminoglycans (GAG)-liydrolases, proteases and lipases.

Keywords

No related keywords in the metadata.

Metrics

Total abstract views: 817
Total article views: 1546

Reader Comments

Before posting a comment, read our privacy policy.

Post a comment (login required)

Crossref Citations

No related citations found.