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Original Research
The blood-brain barrier
Suid-Afrikaanse Tydskrif vir Natuurwetenskap en Tegnologie | Vol 10, No 3 | a498 |
DOI: https://doi.org/10.4102/satnt.v10i3.498
| © 1991 H. S. Meij
| This work is licensed under CC Attribution 4.0
Submitted: 08 July 1991 | Published: 08 July 1991
Submitted: 08 July 1991 | Published: 08 July 1991
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H. S. Meij,, South AfricaFull Text:
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Abstract
The composition of the extracellular fluid (ECF) of the brain is of particular importance, because normal functioning of brain cells depends largely upon a chemically stable fluid environment. Changes in the ECF can lead to serious impairment of brain function. The existence of a barrier between the blood and the brain tissue, by means of which a stable surrounding is maintained, was postulated about 80 years ago and we now know that it resides in the continuous layer of endothelium cells of the brain blood capillaries.
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