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Molecular crosstalk between apoptosis and autophagy induced by a 2-methoxyestradiol analogue (C19) in HeLa cells.
Suid-Afrikaanse Tydskrif vir Natuurwetenskap en Tegnologie | Vol 31, No 1 | a315 |
DOI: https://doi.org/10.4102/satnt.v31i1.315
| © 2012 A. E. Theron, M. Visagie, T. Mqoco, A. Stander, R. Prudent, L. Lafanechere, A. M. Joubert
| This work is licensed under CC Attribution 4.0
Submitted: 26 January 2012 | Published: 03 April 2012
Submitted: 26 January 2012 | Published: 03 April 2012
About the author(s)
A. E. Theron,, South AfricaM. Visagie, University of Pretoria, South Africa
T. Mqoco, University of Pretoria, South Africa
A. Stander, University of Pretoria, South Africa
R. Prudent, University of Pretoria, South Africa
L. Lafanechere, Institut Albert Bonniot, CRI INSERM/UJF U823, France
A. M. Joubert, University of Pretoria, South Africa
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Abstract
Using a novel synthesised sulphamoylated 2-methoxyestradiol analogue, C19, two types of cell death, namely apoptosis and autophagy, were demonstrated in vitro when cervical cancer HeLa cells were exposed to this compound.
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